Mouse Anti-TRADD

Mouse Anti-TRADDFrom:   Santa Cruz Cat. Number:  Rs-1202R  Quantity size:  0.1ml （dilute with pH 7.4 0.01 M PBS or diluent of antibody）  Background: The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins （IAPs） by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. Specificity:  · anti-TRADD is a Mouse monoclonal antibody unconjugated ·specific for TRADD of human ·epitope mapping near the TRADD of human· use for western blotting, elisa, immunoprecipitation   and immunohistochemistry · Protein G affinity chromatography purification, purity :>95%· Isotype: IgG   · mol wt: 92kDa Mouse Anti-TRADD Application: · Western blotting: 1:100-500· Immunohistochemistry: 1:100-500· ELISA: 1:500-1000· Optimal working dilutions must be determined by the end user. Storage:   Store at –20 oC for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20oC. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 oC.  Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Mouse Anti-TRADD